The Smurfs have had an 'interesting' relationship with film of late, and while it hasn't been the most inspiring of kids franchises, these things most certainly seem to be making money. That means they are still getting made.
However, it seems the series is getting a reboot of sorts with Smurfs: The Lost Village, and for those who didn't like the real world portions, rejoice. This is going 'all CG' and seems like it will feature Smurfette as the lead character, looking for her purpose in life. This sounds more the speed of original Smurf fans.
Take a look at the teaser trailer here: