Eh, I dunno. I feel if it was Thanos Marvel would've gone the extra mile and given the words little ridges at the bottom like his chin (Seriously, I think they'd do something like that). Plus, Aaron's never been much of a cosmic story writer.
Not that I have a suggestion as to what it could be, but Thanos doesn't seem to be a fit.
Arkham Asylum, but I like to "Summer" in Coast City.
Given Marvel's new-found emphasis on the cosmic line, Thanos' prominence at the end of the Avengers movie, and the upcoming Guardians of the Galaxy movie, a Thanos title is a safe bet. But I also agree with OwningXylophone that a Genesis series is also a good bet, given Aaron's work on the character in Wolverine and the X-Men.
Let's just hope and pray it isn't yet another solo Wolverine title, esp. not one about his "origins".